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Angiotensin II Reduces Mitochondrial Content in Skeletal Muscle and Affects Glycemic Control

OBJECTIVE—Blockade of angiotensin (Ang) II has been shown to prevent new-onset type 2 diabetes. We focused on the effects of AngII on muscle mitochondria, especially on their biogenesis, as an underlining mechanism of type 2 diabetes. RESEARCH DESIGN AND METHODS—C2C12 cells and C57bl/6 mice were use...

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Detalles Bibliográficos
Autores principales:	Mitsuishi, Masanori, Miyashita, Kazutoshi, Muraki, Ayako, Itoh, Hiroshi
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646070/ https://www.ncbi.nlm.nih.gov/pubmed/19074984 http://dx.doi.org/10.2337/db08-0949

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