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Crucial Role of the CB3-Region of Collagen IV in PARF-Induced Acute Rheumatic Fever
Acute rheumatic fever (ARF) and rheumatic heart disease are serious autoimmune sequelae to infections with Streptococcus pyogenes. Streptococcal M-proteins have been implicated in ARF pathogenesis. Their interaction with collagen type IV (CIV) is a triggering step that induces generation of collagen...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646144/ https://www.ncbi.nlm.nih.gov/pubmed/19252743 http://dx.doi.org/10.1371/journal.pone.0004666 |