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Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo

The ability to detect activation of signaling pathways based solely on gene expression data represents an important goal in biological research. We tested the sensitivity of singular value decomposition-based regression by focusing on functional interactions between the Ras and transforming growth f...

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Detalles Bibliográficos
Autores principales: Liu, Zhandong, Wang, Min, Alvarez, James V, Bonney, Megan E, Chen, Chien-chung, D'Cruz, Celina, Pan, Tien-chi, Tadesse, Mahlet G, Chodosh, Lewis A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646284/
https://www.ncbi.nlm.nih.gov/pubmed/19094238
http://dx.doi.org/10.1186/gb-2008-9-12-r180