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Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo
The ability to detect activation of signaling pathways based solely on gene expression data represents an important goal in biological research. We tested the sensitivity of singular value decomposition-based regression by focusing on functional interactions between the Ras and transforming growth f...
Autores principales: | Liu, Zhandong, Wang, Min, Alvarez, James V, Bonney, Megan E, Chen, Chien-chung, D'Cruz, Celina, Pan, Tien-chi, Tadesse, Mahlet G, Chodosh, Lewis A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646284/ https://www.ncbi.nlm.nih.gov/pubmed/19094238 http://dx.doi.org/10.1186/gb-2008-9-12-r180 |
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