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Releasing the spindle assembly checkpoint without tension
Eukaryotic cells have evolved a spindle assembly checkpoint (SAC) that facilitates accurate genomic segregation during mitosis by delaying anaphase onset in response to errors in kinetochore microtubule attachment. In contrast to the well-studied molecular mechanism by which the SAC blocks anaphase...
Autores principales: | McEwen, Bruce F., Dong, Yimin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646545/ https://www.ncbi.nlm.nih.gov/pubmed/19193624 http://dx.doi.org/10.1083/jcb.200812016 |
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