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Contrasting roles for all-trans retinoic acid in TGF-β–mediated induction of Foxp3 and Il10 genes in developing regulatory T cells

Extrathymic induction of regulatory T (T reg) cells is essential to the regulation of effector T cell responses in the periphery. In addition to Foxp3, T reg cell expression of suppressive cytokines, such as IL-10, is essential for peripheral tolerance, particularly in the intestines. TGF-β has been...

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Detalles Bibliográficos
Autores principales:	Maynard, Craig L., Hatton, Robin D., Helms, Whitney S., Oliver, James R., Stephensen, Charles B., Weaver, Casey T.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646562/ https://www.ncbi.nlm.nih.gov/pubmed/19204112 http://dx.doi.org/10.1084/jem.20080950

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