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Human CD4(+) T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function
CD4(+) recent thymic emigrants (RTEs) comprise a clinically and immunologically important T cell population that indicates thymic output and that is essential for maintaining a diverse αβ–T cell receptor (TCR) repertoire of the naive CD4(+) T cell compartment. However, their frequency and function a...
Autores principales: | Haines, Christopher J., Giffon, Thierry D., Lu, Li-Sheng, Lu, Xiaowei, Tessier-Lavigne, Marc, Ross, Douglas T., Lewis, David B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646563/ https://www.ncbi.nlm.nih.gov/pubmed/19171767 http://dx.doi.org/10.1084/jem.20080996 |
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