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The antigen-specific CD8(+) T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion
Memory T cells exhibit superior responses to pathogens and tumors compared with their naive counterparts. Memory is typically generated via an immune response to a foreign antigen, but functional memory T cells can also be produced from naive cells by homeostatic mechanisms. Using a recently develop...
Autores principales: | Haluszczak, Catherine, Akue, Adovi D., Hamilton, Sara E., Johnson, Lisa D.S., Pujanauski, Lindsey, Teodorovic, Lenka, Jameson, Stephen C., Kedl, Ross M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646575/ https://www.ncbi.nlm.nih.gov/pubmed/19188498 http://dx.doi.org/10.1084/jem.20081829 |
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