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New twist on the regulation of NKG2D ligand expression

The NK cell–activating receptor NKG2D plays a prominent role in antitumor immune responses. Expression of the multiple NKG2D ligands must be tightly controlled to guarantee that NK cells attack tumors but not healthy cells. New data reveal a novel mechanism of posttranslational regulation of the mou...

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Detalles Bibliográficos
Autor principal: Cerwenka, Adelheid
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646580/
https://www.ncbi.nlm.nih.gov/pubmed/19204110
http://dx.doi.org/10.1084/jem.20090225