Cargando…
An update on the toxicity of Aβ in Alzheimer’s disease
Alzheimer’s disease is characterized histopathologically by deposition of insoluble forms of the peptide Aβ and the protein tau in brain. Aβ is the principal component of amyloid plaques and tau of neurofibrillary tangles. Familial cases of AD are associated with causal mutations in the gene encodin...
Autores principales: | Götz, Jürgen, Ittner, Lars M, Schonrock, Nicole, Cappai, Roberto |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646638/ https://www.ncbi.nlm.nih.gov/pubmed/19337449 |
Ejemplares similares
-
Modes of Aβ toxicity in Alzheimer’s disease
por: Götz, Jürgen, et al.
Publicado: (2011) -
Neuronal MicroRNA Deregulation in Response to Alzheimer's Disease Amyloid-β
por: Schonrock, Nicole, et al.
Publicado: (2010) -
Alzheimer's disease models and functional genomics—How many needles are there in the haystack?
por: Götz, Jürgen, et al.
Publicado: (2012) -
Tau aggregation and its interplay with amyloid-β
por: Nisbet, Rebecca M., et al.
Publicado: (2014) -
Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity
por: Eckert, Anne, et al.
Publicado: (2011)