Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes

In the present study, the authors reported on a case in neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) with irreversible organic brain changes. The authors also longitudinally investigated serum brain-derived neurotrophic factor (BDNF) levels in the patient. We found that serum B...

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Autores principales: Ikenouchi-Sugita, Atsuko, Yoshimura, Reiji, Ueda, Nobuhisa, Kodama, Yuki, Umene-Nakano, Wakako, Nakamura, Jun
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646658/
https://www.ncbi.nlm.nih.gov/pubmed/19337469
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author Ikenouchi-Sugita, Atsuko
Yoshimura, Reiji
Ueda, Nobuhisa
Kodama, Yuki
Umene-Nakano, Wakako
Nakamura, Jun
author_facet Ikenouchi-Sugita, Atsuko
Yoshimura, Reiji
Ueda, Nobuhisa
Kodama, Yuki
Umene-Nakano, Wakako
Nakamura, Jun
author_sort Ikenouchi-Sugita, Atsuko
collection PubMed
description In the present study, the authors reported on a case in neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) with irreversible organic brain changes. The authors also longitudinally investigated serum brain-derived neurotrophic factor (BDNF) levels in the patient. We found that serum BDNF levels in the NPSLE patient with irreversible organic brain change were consistently low, independent of the severity of psychiatric symptoms. Thus, the longitudinal measurement of serum BDNF levels might be useful in predicting the prognosis of NPSLE.
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spelling pubmed-26466582009-04-01 Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes Ikenouchi-Sugita, Atsuko Yoshimura, Reiji Ueda, Nobuhisa Kodama, Yuki Umene-Nakano, Wakako Nakamura, Jun Neuropsychiatr Dis Treat Case Report In the present study, the authors reported on a case in neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) with irreversible organic brain changes. The authors also longitudinally investigated serum brain-derived neurotrophic factor (BDNF) levels in the patient. We found that serum BDNF levels in the NPSLE patient with irreversible organic brain change were consistently low, independent of the severity of psychiatric symptoms. Thus, the longitudinal measurement of serum BDNF levels might be useful in predicting the prognosis of NPSLE. Dove Medical Press 2008-12 /pmc/articles/PMC2646658/ /pubmed/19337469 Text en © 2008 Dove Medical Press Limited. All rights reserved
spellingShingle Case Report
Ikenouchi-Sugita, Atsuko
Yoshimura, Reiji
Ueda, Nobuhisa
Kodama, Yuki
Umene-Nakano, Wakako
Nakamura, Jun
Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes
title Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes
title_full Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes
title_fullStr Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes
title_full_unstemmed Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes
title_short Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes
title_sort continuous decrease in serum brain-derived neurotrophic factor (bdnf) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646658/
https://www.ncbi.nlm.nih.gov/pubmed/19337469
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