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Biodistribution and Pharmacokinetic Analysis of Paclitaxel and Ceramide Administered in Multifunctional Polymer-Blend Nanoparticles in Drug Resistant Breast Cancer Model
[Image: see text] In this study, we have investigated the biodistribution and pharmacokinetic analysis of paclitaxel (PTX) and the apoptotic signaling molecule, C(6)-ceramide (CER), when administered in a multifunctional polymer-blend nanoparticle formulation to female nude mice bearing an orthotopi...
Autores principales: | van Vlerken, Lilian E., Duan, Zhenfeng, Little, Steven R., Seiden, Michael V., Amiji, Mansoor M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646668/ https://www.ncbi.nlm.nih.gov/pubmed/18616278 http://dx.doi.org/10.1021/mp800030k |
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