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Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase

[Image: see text] Putrescine (1,4-diaminobutane) activates the autoprocessing and decarboxylation reactions of human S-adenosylmethionine decarboxylase (AdoMetDC), a critical enzyme in the polyamine biosynthetic pathway. In human AdoMetDC, putrescine binds in a buried pocket containing acidic residu...

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Detalles Bibliográficos
Autores principales:	Bale, Shridhar, Lopez, Maria M., Makhatadze, George I., Fang, Qingming, Pegg, Anthony E., Ealick, Steven E.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2008
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646671/ https://www.ncbi.nlm.nih.gov/pubmed/19053272 http://dx.doi.org/10.1021/bi801732m

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