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A Role for Confined Water in Chaperonin Function
[Image: see text] Chaperonins engulf other proteins and accelerate their folding by an unknown mechanism. Here, we combine all-atom molecular dynamics simulations with data from experimental assays of the activity of the bacterial chaperonin GroEL to demonstrate that a chaperonin’s ability to facili...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646679/ https://www.ncbi.nlm.nih.gov/pubmed/18710231 http://dx.doi.org/10.1021/ja802248m |