Cargando…
A new plasmid vector for DNA delivery using lactococci
BACKGROUND: The use of food-grade lactococci as bacterial carriers to DNA delivery into epithelial cells is a new strategy to develop live oral DNA vaccine. Our goal was to develop a new plasmid, named pValac, for antigen delivery for use in lactococci. The pValac plasmid was constructed by the fusi...
Autores principales: | Guimarães, Valeria, Innocentin, Sylvia, Chatel, Jean-Marc, Lefèvre, François, Langella, Philippe, Azevedo, Vasco, Miyoshi, Anderson |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646724/ https://www.ncbi.nlm.nih.gov/pubmed/19208231 http://dx.doi.org/10.1186/1479-0556-7-4 |
Ejemplares similares
-
Lactococci and lactobacilli as mucosal delivery vectors for therapeutic proteins and DNA vaccines
por: Bermúdez-Humarán, Luis G, et al.
Publicado: (2011) -
Immune Response Elicited by DNA Vaccination Using Lactococcus lactis Is Modified by the Production of Surface Exposed Pathogenic Protein
por: Pontes, Daniela, et al.
Publicado: (2014) -
In vitro and in vivo characterization of DNA delivery using recombinant Lactococcus lactis expressing a mutated form of L. monocytogenes Internalin A
por: de Azevedo, Marcela, et al.
Publicado: (2012) -
Production of Fibronectin Binding Protein A at the Surface of Lactococcus lactis Increases Plasmid Transfer In Vitro and In Vivo
por: Pontes, Daniela, et al.
Publicado: (2012) -
Development of Mucosal Vaccines Based on Lactic Acid Bacteria
por: Bermúdez-Humarán, Luis G., et al.
Publicado: (2009)