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Toward a Prostate Specific Antigen-Based Prostate Cancer Diagnostic Assay: Preparation of Keyhole Limpet Hemocyanin -Conjugated Normal and Transformed Prostate Specific Antigen Fragments
[Image: see text] Prostate specific antigen (PSA) molecules secreted by cancerous and normal prostate cells differ in their N-linked glycan composition, while the peptide backbone appears to be conserved. Antibodies selectively recognizing such differentially glycosylated PSA structures could form a...
Autores principales: | Dudkin, Vadim Y., Miller, Justin S., Dudkina, Anna S., Antczak, Christophe, Scheinberg, David A., Danishefsky, Samuel J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646745/ https://www.ncbi.nlm.nih.gov/pubmed/18798614 http://dx.doi.org/10.1021/ja8028137 |
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