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QacR−Cation Recognition Is Mediated by a Redundancy of Residues Capable of Charge Neutralization†

[Image: see text] The Staphylococcus aureus multidrug binding protein QacR binds to a broad spectrum of structurally dissimilar cationic, lipophilic drugs. Our previous structural analyses suggested that five QacR glutamic acid residues are critical for charge neutralization and specification of cer...

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Detalles Bibliográficos
Autores principales:	Peters, Kate M., Schuman, Jason T., Skurray, Ronald A., Brown, Melissa H., Brennan, Richard G., Schumacher, Maria A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2008
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646753/ https://www.ncbi.nlm.nih.gov/pubmed/18616285 http://dx.doi.org/10.1021/bi8008246

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