Inactivation of Cg10062, a cis-3-Chloroacrylic Acid Dehalogenase Homologue in Corynebacterium glutamicum, by (R)- and (S)-Oxirane-2-carboxylate: Analysis and Implications†

[Image: see text] (R)- and (S)-oxirane-2-carboxylate were determined to be active site-directed irreversible inhibitors of the cis-3-chloroacrylic acid dehalogenase (cis-CaaD) homologue Cg10062 found in Corynebacterium glutamicum. Kinetic analysis indicates that the (R) enantiomer binds more tightly...

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Detalles Bibliográficos
Autores principales: Robertson, Brooklyn A., Johnson, William H., Lo, Herng-Hsiang, Whitman, Christian P.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646761/
https://www.ncbi.nlm.nih.gov/pubmed/18646866
http://dx.doi.org/10.1021/bi800790y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646761/
https://www.ncbi.nlm.nih.gov/pubmed/18646866
http://dx.doi.org/10.1021/bi800790y

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