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Inactivation of Cg10062, a cis-3-Chloroacrylic Acid Dehalogenase Homologue in Corynebacterium glutamicum, by (R)- and (S)-Oxirane-2-carboxylate: Analysis and Implications†
[Image: see text] (R)- and (S)-oxirane-2-carboxylate were determined to be active site-directed irreversible inhibitors of the cis-3-chloroacrylic acid dehalogenase (cis-CaaD) homologue Cg10062 found in Corynebacterium glutamicum. Kinetic analysis indicates that the (R) enantiomer binds more tightly...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646761/ https://www.ncbi.nlm.nih.gov/pubmed/18646866 http://dx.doi.org/10.1021/bi800790y |