Low-Density Lipoprotein Has an Enormous Capacity To Bind (E)-4-Hydroxynon-2-enal (HNE): Detection and Characterization of Lysyl and Histidyl Adducts Containing Multiple Molecules of HNE

[Image: see text] (E)-4-Hydroxynon-2-enal (HNE), an electrophilic bifunctional cytotoxic lipid peroxidation product, forms covalent adducts with nucleophilic side chains of amino acid residues. HNE-derived adducts have been implicated in many pathophysiological processes including atherosclerosis, d...

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Detalles Bibliográficos
Autores principales: Annangudi, Suresh P., Deng, Yijun, Gu, Xiaorong, Zhang, Wujuan, Crabb, John W., Salomon, Robert G.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646868/
https://www.ncbi.nlm.nih.gov/pubmed/18570390
http://dx.doi.org/10.1021/tx8000303

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