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Role of Insulin and Growth Hormone/Insulin-Like Growth Factor-I Signaling in Lifespan Extension: Rodent Longevity Models for Studying Aging and Calorie Restriction

Insulin/insulin-like growth factor-I (IGF-I) pathways are recognized as critical signaling pathways involved in the control of lifespans in lower organisms to mammals. Caloric restriction (CR) reduces plasma concentration of insulin, growth hormone (GH), and IGF-I. CR retards various age-dependent d...

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Detalles Bibliográficos
Autores principales:	Chiba, T, Yamaza, H, Shimokawa, I
Formato:	Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers Ltd. 2007
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647154/ https://www.ncbi.nlm.nih.gov/pubmed/19412415 http://dx.doi.org/10.2174/138920207783591726

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