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Model-based probe set optimization for high-performance microarrays

A major challenge in microarray design is the selection of highly specific oligonucleotide probes for all targeted genes of interest, while maintaining thermodynamic uniformity at the hybridization temperature. We introduce a novel microarray design framework (Thermodynamic Model-based Oligo Design...

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Detalles Bibliográficos
Autores principales:	Leparc, Germán Gastón, Tüchler, Thomas, Striedner, Gerald, Bayer, Karl, Sykacek, Peter, Hofacker, Ivo L., Kreil, David P.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647282/ https://www.ncbi.nlm.nih.gov/pubmed/19103659 http://dx.doi.org/10.1093/nar/gkn1001

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