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Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity
Guanine-rich nucleic acids can form G-quadruplexes that are important in gene regulation, biosensor design and nano-structure construction. In this article, we report on the development of a nanopore encapsulating single-molecule method for exploring how cations regulate the folding and unfolding of...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647319/ https://www.ncbi.nlm.nih.gov/pubmed/19112078 http://dx.doi.org/10.1093/nar/gkn968 |