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Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study

OBJECTIVE—To estimate the prevalence and incidence of diabetes, clinical characteristics, and risk factors for chronic complications among Navajo youth, using data collected by the SEARCH for Diabetes in Youth Study (SEARCH study). RESEARCH DESIGN AND METHODS—The SEARCH study identified all prevalen...

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Autores principales: Dabelea, Dana, DeGroat, Joquetta, Sorrelman, Carmelita, Glass, Martia, Percy, Christopher A., Avery, Charlene, Hu, Diana, D'Agostino, Ralph B., Beyer, Jennifer, Imperatore, Giuseppina, Testaverde, Lisa, Klingensmith, Georgeanna, Hamman, Richard F.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647690/
https://www.ncbi.nlm.nih.gov/pubmed/19246579
http://dx.doi.org/10.2337/dc09-S206
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author Dabelea, Dana
DeGroat, Joquetta
Sorrelman, Carmelita
Glass, Martia
Percy, Christopher A.
Avery, Charlene
Hu, Diana
D'Agostino, Ralph B.
Beyer, Jennifer
Imperatore, Giuseppina
Testaverde, Lisa
Klingensmith, Georgeanna
Hamman, Richard F.
author_facet Dabelea, Dana
DeGroat, Joquetta
Sorrelman, Carmelita
Glass, Martia
Percy, Christopher A.
Avery, Charlene
Hu, Diana
D'Agostino, Ralph B.
Beyer, Jennifer
Imperatore, Giuseppina
Testaverde, Lisa
Klingensmith, Georgeanna
Hamman, Richard F.
author_sort Dabelea, Dana
collection PubMed
description OBJECTIVE—To estimate the prevalence and incidence of diabetes, clinical characteristics, and risk factors for chronic complications among Navajo youth, using data collected by the SEARCH for Diabetes in Youth Study (SEARCH study). RESEARCH DESIGN AND METHODS—The SEARCH study identified all prevalent cases of diabetes in 2001 and all incident cases in 2002–2005 among Navajo youth. We estimated denominators with the user population for eligible health care facilities. Youth with diabetes also attended a research visit that included questionnaires, physical examination, blood and urine collection, and extended medical record abstraction. RESULTS—Diabetes is infrequent among Navajo youth aged <10 years. However, both prevalence and incidence of diabetes are high in older youth. Among adolescents aged 15–19 years, 1 in 359 Navajo youth had diabetes in 2001 and 1 in 2,542 developed diabetes annually. The vast majority of diabetes among Navajo youth with diabetes is type 2, although type 1 diabetes is also present, especially among younger children. Navajo youth with either diabetes type were likely to have poor glycemic control, high prevalence of unhealthy behaviors, and evidence of severely depressed mood. Youth with type 2 diabetes had more metabolic factors associated with obesity and insulin resistance (abdominal fat deposition, dyslipidemia, and higher albumin-to-creatinine ratio) than youth with type 1 diabetes. CONCLUSIONS—Our data provide evidence that diabetes is an important health problem for Navajo youth. Targeted efforts aimed at primary prevention of diabetes in Navajo youth and efforts to prevent or delay the development of chronic complications among those with diabetes are warranted.
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spelling pubmed-26476902010-03-01 Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study Dabelea, Dana DeGroat, Joquetta Sorrelman, Carmelita Glass, Martia Percy, Christopher A. Avery, Charlene Hu, Diana D'Agostino, Ralph B. Beyer, Jennifer Imperatore, Giuseppina Testaverde, Lisa Klingensmith, Georgeanna Hamman, Richard F. Diabetes Care Articles OBJECTIVE—To estimate the prevalence and incidence of diabetes, clinical characteristics, and risk factors for chronic complications among Navajo youth, using data collected by the SEARCH for Diabetes in Youth Study (SEARCH study). RESEARCH DESIGN AND METHODS—The SEARCH study identified all prevalent cases of diabetes in 2001 and all incident cases in 2002–2005 among Navajo youth. We estimated denominators with the user population for eligible health care facilities. Youth with diabetes also attended a research visit that included questionnaires, physical examination, blood and urine collection, and extended medical record abstraction. RESULTS—Diabetes is infrequent among Navajo youth aged <10 years. However, both prevalence and incidence of diabetes are high in older youth. Among adolescents aged 15–19 years, 1 in 359 Navajo youth had diabetes in 2001 and 1 in 2,542 developed diabetes annually. The vast majority of diabetes among Navajo youth with diabetes is type 2, although type 1 diabetes is also present, especially among younger children. Navajo youth with either diabetes type were likely to have poor glycemic control, high prevalence of unhealthy behaviors, and evidence of severely depressed mood. Youth with type 2 diabetes had more metabolic factors associated with obesity and insulin resistance (abdominal fat deposition, dyslipidemia, and higher albumin-to-creatinine ratio) than youth with type 1 diabetes. CONCLUSIONS—Our data provide evidence that diabetes is an important health problem for Navajo youth. Targeted efforts aimed at primary prevention of diabetes in Navajo youth and efforts to prevent or delay the development of chronic complications among those with diabetes are warranted. American Diabetes Association 2009-03 /pmc/articles/PMC2647690/ /pubmed/19246579 http://dx.doi.org/10.2337/dc09-S206 Text en Copyright © 2009, American Diabetes Association Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.
spellingShingle Articles
Dabelea, Dana
DeGroat, Joquetta
Sorrelman, Carmelita
Glass, Martia
Percy, Christopher A.
Avery, Charlene
Hu, Diana
D'Agostino, Ralph B.
Beyer, Jennifer
Imperatore, Giuseppina
Testaverde, Lisa
Klingensmith, Georgeanna
Hamman, Richard F.
Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
title Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
title_full Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
title_fullStr Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
title_full_unstemmed Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
title_short Diabetes in Navajo Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study
title_sort diabetes in navajo youth: prevalence, incidence, and clinical characteristics: the search for diabetes in youth study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647690/
https://www.ncbi.nlm.nih.gov/pubmed/19246579
http://dx.doi.org/10.2337/dc09-S206
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