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Detection of Alpha-Rod Protein Repeats Using a Neural Network and Application to Huntingtin

A growing number of solved protein structures display an elongated structural domain, denoted here as alpha-rod, composed of stacked pairs of anti-parallel alpha-helices. Alpha-rods are flexible and expose a large surface, which makes them suitable for protein interaction. Although most likely origi...

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Detalles Bibliográficos
Autores principales: Palidwor, Gareth A., Shcherbinin, Sergey, Huska, Matthew R., Rasko, Tamas, Stelzl, Ulrich, Arumughan, Anup, Foulle, Raphaele, Porras, Pablo, Sanchez-Pulido, Luis, Wanker, Erich E., Andrade-Navarro, Miguel A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647740/
https://www.ncbi.nlm.nih.gov/pubmed/19282972
http://dx.doi.org/10.1371/journal.pcbi.1000304