Molecular Analysis of Activation-Induced Cytidine Deaminase Gene in Immunoglobulin-E Deficient Patients

Understanding how class switch recombination (CSR) is regulated to produce immunoglobulin E (IgE) has become fundamental because of the dramatic increase in the prevalence of IgE-mediated hypersensitivity reactions. CSR requires the induction of the enzyme AICDA in B cells. Mutations in AICDA have b...

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Detalles Bibliográficos
Autores principales: Roa, Sergio, Isidoro-Garcia, Maria, Davila, Ignacio, Laffond, Elena, Lorente, Felix, Gonzalez-Sarmiento, Rogelio
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647753/
https://www.ncbi.nlm.nih.gov/pubmed/19266080
http://dx.doi.org/10.1155/2008/146715

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