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Mef2-mediated transcription of the miR379–410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels
Neuronal activity orchestrates the proper development of the neuronal circuitry by regulating both transcriptional and post-transcriptional gene expression programmes. How these programmes are coordinated, however, is largely unknown. We found that the transcription of miR379–410, a large cluster of...
Autores principales: | Fiore, Roberto, Khudayberdiev, Sharof, Christensen, Mette, Siegel, Gabriele, Flavell, Steven W, Kim, Tae-Kyung, Greenberg, Michael E, Schratt, Gerhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647767/ https://www.ncbi.nlm.nih.gov/pubmed/19197241 http://dx.doi.org/10.1038/emboj.2009.10 |
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