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HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice
Hepatitis C virus (HCV) is a blood-borne pathogen and a major cause of liver disease worldwide. Gene expression profiling was used to characterize the transcriptional response to HCV H77c infection. Evidence is presented for activation of innate antiviral signaling pathways as well as induction of l...
Autores principales: | Joyce, Michael A., Walters, Kathie-Anne, Lamb, Sue-Ellen, Yeh, Mathew M., Zhu, Lin-Fu, Kneteman, Norman, Doyle, Jason S., Katze, Michael G., Tyrrell, D. Lorne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647842/ https://www.ncbi.nlm.nih.gov/pubmed/19242562 http://dx.doi.org/10.1371/journal.ppat.1000291 |
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