Immunomodulatory effects of recombinant BCG expressing pertussis toxin on TNF-alpha and IL-10 in a bladder cancer model

BACKGROUND: Since successful treatment of superficial bladder cancer with BCG requires proper induction of Th1 immunity, we have developed a rBCG-S1PT strain that induced a stronger cellular immune response than BCG. This preclinical study was designed to compare the modulatory effects of BCG and rB...

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Detalles Bibliográficos
Autores principales: Chade, Daher C, Borra, Ricardo C, Nascimento, Ivan P, Villanova, Fabiola E, Leite, Luciana CC, Andrade, Enrico, Srougi, Miguel, Ramos, Kátia L, Andrade, Priscila M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647907/
https://www.ncbi.nlm.nih.gov/pubmed/19040745
http://dx.doi.org/10.1186/1756-9966-27-78

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