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Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report

INTRODUCTION: Jorge Lobo's disease (Lacaziosis) is a subcutaneous infection of humans living in the Amazon region of Latin America, and in dolphins inhabiting the east coastal areas of the United States. The disease mainly affects people from rural areas living or working in close contact with...

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Autores principales: Rosa, Patrícia Sammarco, Soares, Cleverson Teixeira, Belone, Andréa de Faria Fernandes, Vilela, Raquel, Ura, Somei, Filho, Milton Cury, Mendoza, Leonel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647936/
https://www.ncbi.nlm.nih.gov/pubmed/19220901
http://dx.doi.org/10.1186/1752-1947-3-67
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author Rosa, Patrícia Sammarco
Soares, Cleverson Teixeira
Belone, Andréa de Faria Fernandes
Vilela, Raquel
Ura, Somei
Filho, Milton Cury
Mendoza, Leonel
author_facet Rosa, Patrícia Sammarco
Soares, Cleverson Teixeira
Belone, Andréa de Faria Fernandes
Vilela, Raquel
Ura, Somei
Filho, Milton Cury
Mendoza, Leonel
author_sort Rosa, Patrícia Sammarco
collection PubMed
description INTRODUCTION: Jorge Lobo's disease (Lacaziosis) is a subcutaneous infection of humans living in the Amazon region of Latin America, and in dolphins inhabiting the east coastal areas of the United States. The disease mainly affects people from rural areas living or working in close contact with vegetation and aquatic environments. Most patients refer having developed lesions after accidental trauma with plant thorns or insect bites. Inter-human transmission has never been confirmed suggesting that Lacazia loboi is acquired from environmental propagules. CASE PRESENTATION: We report the case of a 41-year-old woman from São Paulo, Brazil, a non-endemic area of Jorge Lobo's disease, with L. loboi skin infection most likely accidentally acquired while manipulating experimentally infected mice in the laboratory. CONCLUSION: Because many patients with Jorge Lobo's disease do not recall accidental skin trauma before their infections, the possibility of accidentally acquired Jorge Lobo's disease through unnoticed broken skin should be considered during the clinical investigation of nodular skin diseases in people who have contact with the fungus or who live in endemic areas. This is the second report of animal to human transmission of this disease.
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spelling pubmed-26479362009-02-26 Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report Rosa, Patrícia Sammarco Soares, Cleverson Teixeira Belone, Andréa de Faria Fernandes Vilela, Raquel Ura, Somei Filho, Milton Cury Mendoza, Leonel J Med Case Reports Case report INTRODUCTION: Jorge Lobo's disease (Lacaziosis) is a subcutaneous infection of humans living in the Amazon region of Latin America, and in dolphins inhabiting the east coastal areas of the United States. The disease mainly affects people from rural areas living or working in close contact with vegetation and aquatic environments. Most patients refer having developed lesions after accidental trauma with plant thorns or insect bites. Inter-human transmission has never been confirmed suggesting that Lacazia loboi is acquired from environmental propagules. CASE PRESENTATION: We report the case of a 41-year-old woman from São Paulo, Brazil, a non-endemic area of Jorge Lobo's disease, with L. loboi skin infection most likely accidentally acquired while manipulating experimentally infected mice in the laboratory. CONCLUSION: Because many patients with Jorge Lobo's disease do not recall accidental skin trauma before their infections, the possibility of accidentally acquired Jorge Lobo's disease through unnoticed broken skin should be considered during the clinical investigation of nodular skin diseases in people who have contact with the fungus or who live in endemic areas. This is the second report of animal to human transmission of this disease. BioMed Central 2009-02-16 /pmc/articles/PMC2647936/ /pubmed/19220901 http://dx.doi.org/10.1186/1752-1947-3-67 Text en Copyright ©2009 Rosa et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case report
Rosa, Patrícia Sammarco
Soares, Cleverson Teixeira
Belone, Andréa de Faria Fernandes
Vilela, Raquel
Ura, Somei
Filho, Milton Cury
Mendoza, Leonel
Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report
title Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report
title_full Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report
title_fullStr Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report
title_full_unstemmed Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report
title_short Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report
title_sort accidental jorge lobo's disease in a worker dealing with lacazia loboi infected mice: a case report
topic Case report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647936/
https://www.ncbi.nlm.nih.gov/pubmed/19220901
http://dx.doi.org/10.1186/1752-1947-3-67
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