Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression

BACKGROUND: Microsatellite instability (MSI) refers to mutations in short motifs of tandemly repeated nucleotides resulting from replication errors and deficient mismatch repair (MMR). Colorectal cancer with MSI has characteristic biology and chemosensitivity, however the molecular basis remains unc...

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Detalles Bibliográficos
Autores principales: Jensen, Søren A, Vainer, Ben, Kruhøffer, Mogens, Sørensen, Jens B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647942/
https://www.ncbi.nlm.nih.gov/pubmed/19154585
http://dx.doi.org/10.1186/1471-2407-9-25

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