Ca(2+) channels in retinal pigment epithelial cells regulate vascular endothelial growth factor secretion rates in health and disease

PURPOSE: Choroidal neovascularization (CNV) is the most severe complication in age-related macular degeneration. The major angiogenic factor involved is vascular endothelial growth factor (VEGF) secreted by the retinal pigment epithelium (RPE). Since RPE cells express neuroendocrine L-type Ca(2+) ch...

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Detalles Bibliográficos
Autores principales: Rosenthal, Rita, Heimann, Heinrich, Agostini, Hansjürgen, Martin, Gottfried, Hansen, Lutz Lothar, Strauss, Olaf
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647973/
https://www.ncbi.nlm.nih.gov/pubmed/17417605

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