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IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein

BACKGROUND: The recently identified member of the TNF superfamily TL1A (TNFSF15) increases IFN-γ production by T cells in peripheral and mucosal CCR9+ T cells. TL1A and its receptor DR3 are up-regulated during chronic intestinal inflammation in ulcerative colitis and Crohn's disease (CD). TL1A...

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Detalles Bibliográficos
Autores principales:	Michelsen, Kathrin S., Thomas, Lisa S., Taylor, Kent D., Yu, Qi T., Mei, Ling, Landers, Carol J., Derkowski, Carrie, McGovern, Dermot P. B., Rotter, Jerome I., Targan, Stephan R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648040/ https://www.ncbi.nlm.nih.gov/pubmed/19262684 http://dx.doi.org/10.1371/journal.pone.0004719

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