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PCA-based population structure inference with generic clustering algorithms

BACKGROUND: Handling genotype data typed at hundreds of thousands of loci is very time-consuming and it is no exception for population structure inference. Therefore, we propose to apply PCA to the genotype data of a population, select the significant principal components using the Tracy-Widom distr...

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Detalles Bibliográficos
Autores principales: Lee, Chih, Abdool, Ali, Huang, Chun-Hsi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648762/
https://www.ncbi.nlm.nih.gov/pubmed/19208178
http://dx.doi.org/10.1186/1471-2105-10-S1-S73