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Pyrrolysyl-tRNA synthetase:tRNA(Pyl) structure reveals the molecular basis of orthogonality

Pyrrolysine (Pyl), the 22(nd) natural amino acid, is genetically encoded by UAG and inserted into proteins by the unique suppressor tRNA(Pyl)1. The Methanosarcinaceae produce Pyl and express Pyl-containing methyltransferases that allow growth on methylamines2. Homologous methyltransferases and the P...

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Detalles Bibliográficos
Autores principales:	Nozawa, Kayo, O’Donoghue, Patrick, Gundllapalli, Sarath, Araiso, Yuhei, Ishitani, Ryuichiro, Umehara, Takuya, Soll, Dieter, Nureki, Osamu
Formato:	Texto
Lenguaje:	English
Publicado:	2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648862/ https://www.ncbi.nlm.nih.gov/pubmed/19118381 http://dx.doi.org/10.1038/nature07611

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