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Expansion of the human μ-opioid receptor gene architecture: novel functional variants

The μ-opioid receptor (OPRM1) is the principal receptor target for both endogenous and exogenous opioid analgesics. There are substantial individual differences in human responses to painful stimuli and to opiate drugs that are attributed to genetic variations in OPRM1. In searching for new function...

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Detalles Bibliográficos
Autores principales:	Shabalina, Svetlana A., Zaykin, Dmitri V., Gris, Pavel, Ogurtsov, Aleksey Y., Gauthier, Josee, Shibata, Kyoko, Tchivileva, Inna E., Belfer, Inna, Mishra, Bikashkumar, Kiselycznyk, Carly, Wallace, Margaret R., Staud, Roland, Spiridonov, Nikolay A., Max, Mitchell B., Goldman, David, Fillingim, Roger B., Maixner, William, Diatchenko, Luda
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649019/ https://www.ncbi.nlm.nih.gov/pubmed/19103668 http://dx.doi.org/10.1093/hmg/ddn439

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