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Silencing of the Transforming Growth Factor-β (TGFβ) Receptor II by Krüppel-like Factor 14 Underscores the Importance of a Negative Feedback Mechanism in TGFβ Signaling

The role of non-Smad proteins in the regulation of transforming growth factor-β (TGFβ) signaling is an emerging line of active investigation. Here, we characterize the role of KLF14, as a TGFβ-inducible, non-Smad protein that silences the TGFβ receptor II (TGFβRII) promoter. Together with endocytosi...

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Detalles Bibliográficos
Autores principales:	Truty, Mark J., Lomberk, Gwen, Fernandez-Zapico, Martin E., Urrutia, Raul
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Transcription, Chromatin, and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649086/ https://www.ncbi.nlm.nih.gov/pubmed/19088080 http://dx.doi.org/10.1074/jbc.M807791200

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