Cargando…

Identification of a potent herbal molecule for the treatment of breast cancer

BACKGROUND: Breast cancer (BCa)-related mortality still remains the second leading cause of cancer-related deaths worldwide. Patients with BCa have increasingly shown resistance and high toxicity to current chemotherapeutic drugs for which identification of novel targeted therapies are required. MET...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koduru, Srinivas, Sowmyalakshmi, Srinivasan, Kumar, Raj, Gomathinayagam, Rohini, Rohr, Jürgen, Damodaran, Chendil
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649156/ https://www.ncbi.nlm.nih.gov/pubmed/19183448 http://dx.doi.org/10.1186/1471-2407-9-41

Ejemplares similares

11-Deoxylandomycinone and landomycins X-Z, new cytotoxic angucyclin(on)es from a Streptomyces cyanogenus K62 mutant strain
por: Shaaban, Khaled A., et al.
Publicado: (2010)

A small molecule inhibitor of Notch1 modulates stemness and suppresses breast cancer cell growth
por: Saran, Uttara, et al.
Publicado: (2023)

Corrigendum: A small molecule inhibitor of Notch1 modulates stemness and suppresses breast cancer cell growth
por: Saran, Uttara, et al.
Publicado: (2023)

Molecular insights: Suppression of EGFR and AKT activation by a small molecule in non-small cell lung cancer
por: Chandrasekaran, Balaji, et al.
Publicado: (2017)

A Review on Notch Signaling and Colorectal Cancer
por: Tyagi, Ashish, et al.
Publicado: (2020)

ASR488, a novel small molecule, activates an mRNA binding protein, CPEB1, and inhibits the growth of bladder cancer
por: Tyagi, Ashish, et al.
Publicado: (2020)

Herbal Medicine Is Potent Estrogen
Publicado: (1999)

Recent Advances in the Chemistry and Therapeutic Evaluation of Naturally Occurring and Synthetic Withanolides
por: Singh, Amandeep, et al.
Publicado: (2022)

A Comprehensive Transcriptomic Analysis of Arsenic-Induced Bladder Carcinogenesis
por: Shukla, Vaibhav, et al.
Publicado: (2022)

Indian Herbal Medicines: Possible Potent Therapeutic Agents for Rheumatoid Arthritis
por: Rathore, Brijesh, et al.
Publicado: (2007)

Extensive screening for herbal extracts with potent antioxidant properties
por: Niwano, Yoshimi, et al.
Publicado: (2011)

Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells
por: Suman, Suman, et al.
Publicado: (2016)

Potent natural products and herbal medicines for treating liver fibrosis
por: Chen, Shao-Ru, et al.
Publicado: (2015)

Identification of potent and selective small molecule inhibitors of the cation channel TRPM4
por: Ozhathil, Lijo Cherian, et al.
Publicado: (2018)

Identification of potent small molecule inhibitors of SARS-CoV-2 entry
por: Mediouni, Sonia, et al.
Publicado: (2022)

Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer
por: Pal, Deeksha, et al.
Publicado: (2018)

Bioactive Natural Molecules and Traditional Herbal Medicine in the Treatment of Airways Diseases
por: Rogerio, Alexandre de Paula, et al.
Publicado: (2016)

Small molecules of herbal origin for osteoarthritis treatment: in vitro and in vivo evidence
por: Zhang, Penghui, et al.
Publicado: (2022)

Withaferin A Inhibits Prostate Carcinogenesis in a PTEN-deficient Mouse Model of Prostate Cancer()()
por: Moselhy, Jim, et al.
Publicado: (2017)

Identification and characterization of potent small molecule inhibitor of hemorrhagic fever New World arenaviruses
por: Bolken, Tove′ C., et al.
Publicado: (2006)

Spiro[pyrrolidine-3, 3´-oxindole] as potent anti-breast cancer compounds: Their design, synthesis, biological evaluation and cellular target identification
por: Hati, Santanu, et al.
Publicado: (2016)

Chinese Herbal Medicine in the Treatment of Depression in Parkinson’s Disease: From Molecules to Systems
por: Zhang, Yi, et al.
Publicado: (2022)

Oral administration of withaferin A inhibits carcinogenesis of prostate in TRAMP model
por: Suman, Suman, et al.
Publicado: (2016)

Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration
por: Gomathinayagam, Rohini, et al.
Publicado: (2014)

Carriers of the TCF7L2 rs7903146, rs12255372 Risk Alleles in the South Tamil Nadu T2DM Patients Present with Early Incidence and Insulin Dependence
por: Velayutham, Kumaravel, et al.
Publicado: (2019)

Prevention of cadmium bioaccumulation by herbal adaptogens
por: Bharavi, K., et al.
Publicado: (2011)

Identification of a potent small molecule capable of regulating polyploidization, megakaryocyte maturation, and platelet production
por: Huang, Nick, et al.
Publicado: (2016)

Herbal Medicines for the Treatment of Nonalcoholic Steatohepatitis: Current Scenario and Future Prospects
por: Jadeja, Ravirajsinh, et al.
Publicado: (2014)

Hepatoprotective Potential of Herbal Medicine
por: Jadeja, Ravirajsinh, et al.
Publicado: (2015)

Targeting of the breast cancer microenvironment with a potent and linkable oxindole based antiangiogenic small molecule
por: Argyros, Orestis, et al.
Publicado: (2017)

Synthesis of potent MDA-MB 231 breast cancer drug molecules from single step
por: Govindaraj, Senthilnathan, et al.
Publicado: (2023)

Antiandrogen-Equipped Histone Deacetylase Inhibitors Selectively Inhibit Androgen Receptor (AR) and AR-Splice Variant (AR-SV) in Castration-Resistant Prostate Cancer (CRPC)
por: Chandrasekaran, Balaji, et al.
Publicado: (2023)

Identification of Verrucarin A as a Potent and Selective Steroid Receptor Coactivator-3 Small Molecule Inhibitor
por: Yan, Fei, et al.
Publicado: (2014)

Determinant role for the gep oncogenes, Gα12/13, in ovarian cancer cell proliferation and xenograft tumor growth
por: Ha, Ji Hee, et al.
Publicado: (2015)

Epitope Identification and Designing a Potent Multi-epitope Vaccine Construct against SARS-CoV-2 Including the Emerging Variants
por: Srinivasan, Sivasubramanian, et al.
Publicado: (2022)

Activation of AKT negatively regulates the pro-apoptotic function of death-associated protein kinase 3 (DAPK3) in prostate cancer
por: Das, Trinath P., et al.
Publicado: (2016)

Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis
por: Pal, Deeksha, et al.
Publicado: (2017)

Human-Induced Pluripotent Stem Cells and Herbal Small-Molecule Drugs for Treatment of Alzheimer’s Disease
por: Wuli, Wei, et al.
Publicado: (2020)

Noncoding RNAs: key molecules in understanding and treating pain
por: Bali, Kiran Kumar, et al.
Publicado: (2014)

Chemopreventive and Anticancer Effects of Thymoquinone: Cellular and Molecular Targets
por: Gomathinayagam, Rohini, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ijhbpte3ctmp14afc14aed2ohb