Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer

BACKGROUND: It has been suggested that the single nucleotide polymorphism 309 (SNP309, T -> G) in the promoter region of the MDM2 gene is important for tumor development; however, with regards to breast cancer, inconsistent associations have been reported worldwide. It is speculated that these co...

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Detalles Bibliográficos
Autores principales: Sun, Ying-Fang, Leu, Jyh-Der, Chen, Su-Mei, Lin, I-Feng, Lee, Yi-Jang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649157/
https://www.ncbi.nlm.nih.gov/pubmed/19144119
http://dx.doi.org/10.1186/1471-2407-9-13

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