Investigation of founder effects for the Thr377Met Myocilin mutation in glaucoma families from differing ethnic backgrounds

PURPOSE: The aim of this study was to determine if there is a common founder for the Thr377Met myocilin mutation in primary open angle glaucoma (POAG) families with various ethnic backgrounds. METHODS: Genomic DNA of 24 POAG-affected individuals from nine pedigrees with the Thr377Met mutation and 10...

Descripción completa

Detalles Bibliográficos
Autores principales: Hewitt, Alex W., Samples, John R., Allingham, R. Rand, Järvelä, Irma, Kitsos, George, Krishnadas, Subbaiah R., Richards, Julia E., Lichter, Paul R., Petersen, Michael B., Sundaresan, Periasamy, Wiggs, Janey L., Mackey, David A., Wirtz, Mary K.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649311/
https://www.ncbi.nlm.nih.gov/pubmed/17417609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649311/
https://www.ncbi.nlm.nih.gov/pubmed/17417609

Ejemplares similares