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Hypoxia Alters Cell Cycle Regulatory Protein Expression and Induces Premature Maturation of Oligodendrocyte Precursor Cells

BACKGROUND: Periventricular white matter injury (PWMI) is a common form of brain injury sustained by preterm infants. A major factor that predisposes to PWMI is hypoxia. Because oligodendrocytes (OLs) are responsible for myelination of axons, abnormal OL development or function may affect brain myel...

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Detalles Bibliográficos
Autores principales: Akundi, Ravi Shankar, Rivkees, Scott A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649433/
https://www.ncbi.nlm.nih.gov/pubmed/19270736
http://dx.doi.org/10.1371/journal.pone.0004739