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A New Strategy to Generate Functional Insulin-Producing Cell Lines by Somatic Gene Transfer into Pancreatic Progenitors

BACKGROUND: There is increasing interest in developing human cell lines to be used to better understand cell biology, but also for drug screening, toxicology analysis and future cell therapy. In the endocrine pancreatic field, functional human beta cell lines are extremely scarce. On the other hand,...

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Detalles Bibliográficos
Autores principales: Ravassard, Philippe, Emilie Bricout-Neveu, Hazhouz, Yasmine, Pechberty, Severine, Mallet, Jacques, Czernichow, Paul, Scharfmann, Raphael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649535/
https://www.ncbi.nlm.nih.gov/pubmed/19266046
http://dx.doi.org/10.1371/journal.pone.0004731