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A New Strategy to Generate Functional Insulin-Producing Cell Lines by Somatic Gene Transfer into Pancreatic Progenitors
BACKGROUND: There is increasing interest in developing human cell lines to be used to better understand cell biology, but also for drug screening, toxicology analysis and future cell therapy. In the endocrine pancreatic field, functional human beta cell lines are extremely scarce. On the other hand,...
Autores principales: | Ravassard, Philippe, Emilie Bricout-Neveu, Hazhouz, Yasmine, Pechberty, Severine, Mallet, Jacques, Czernichow, Paul, Scharfmann, Raphael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649535/ https://www.ncbi.nlm.nih.gov/pubmed/19266046 http://dx.doi.org/10.1371/journal.pone.0004731 |
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