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Big Genomes Facilitate the Comparative Identification of Regulatory Elements

The identification of regulatory sequences in animal genomes remains a significant challenge. Comparative genomic methods that use patterns of evolutionary conservation to identify non-coding sequences with regulatory function have yielded many new vertebrate enhancers. However, these methods have n...

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Detalles Bibliográficos
Autores principales: Peterson, Brant K., Hare, Emily E., Iyer, Venky N., Storage, Steven, Conner, Laura, Papaj, Daniel R., Kurashima, Rick, Jang, Eric, Eisen, Michael B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650094/
https://www.ncbi.nlm.nih.gov/pubmed/19259274
http://dx.doi.org/10.1371/journal.pone.0004688