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Big Genomes Facilitate the Comparative Identification of Regulatory Elements
The identification of regulatory sequences in animal genomes remains a significant challenge. Comparative genomic methods that use patterns of evolutionary conservation to identify non-coding sequences with regulatory function have yielded many new vertebrate enhancers. However, these methods have n...
Autores principales: | Peterson, Brant K., Hare, Emily E., Iyer, Venky N., Storage, Steven, Conner, Laura, Papaj, Daniel R., Kurashima, Rick, Jang, Eric, Eisen, Michael B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650094/ https://www.ncbi.nlm.nih.gov/pubmed/19259274 http://dx.doi.org/10.1371/journal.pone.0004688 |
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