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Meta-Analysis and Gene Set Enrichment Relative to ER Status Reveal Elevated Activity of MYC and E2F in the “Basal” Breast Cancer Subgroup

BACKGROUND: Breast cancers lacking the estrogen receptor (ER) can be distinguished from other breast cancers on the basis of poor prognosis, high grade, distinctive histopathology and unique molecular signatures. These features further distinguish estrogen receptor negative (ER−) tumor subtypes, but...

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Detalles Bibliográficos
Autores principales: Alles, M. Chehani, Gardiner-Garden, Margaret, Nott, David J., Wang, Yixin, Foekens, John A., Sutherland, Robert L., Musgrove, Elizabeth A., Ormandy, Christopher J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650420/
https://www.ncbi.nlm.nih.gov/pubmed/19270750
http://dx.doi.org/10.1371/journal.pone.0004710

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