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Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery

Regulatory T (T(reg)) cells expressing forkhead box P3 (Foxp3) arise during thymic selection among thymocytes with modestly self-reactive T cell receptors. In vitro studies suggest Foxp3 can also be induced among peripheral CD4(+) T cells in a cytokine dependent manner. T(reg) cells of thymic or per...

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Detalles Bibliográficos
Autores principales:	Barnes, Michael J, Krebs, Philippe, Harris, Nathaniel, Eidenschenk, Celine, Gonzalez-Quintial, Rosana, Arnold, Carrie N, Crozat, Karine, Sovath, Sosathya, Moresco, Eva Marie, Theofilopoulos, Argyrios N, Beutler, Bruce, Hoebe, Kasper
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650725/ https://www.ncbi.nlm.nih.gov/pubmed/19260764 http://dx.doi.org/10.1371/journal.pbio.1000051

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