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Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report

An eleven month old girl presented with chronic urticaria since three months of age. There was a generalised hyperpigmented maculo-papular rash. Darier sign was positive. The skin biopsy showed plenty of spindle shaped mast cells with eosinophilic cytoplasm infiltrating the dermis and the appendicea...

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Autores principales: Tamhankar, Parag M, Suvarna, Jyoti, Deshmukh, Chandrahas T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651115/
https://www.ncbi.nlm.nih.gov/pubmed/19154597
http://dx.doi.org/10.1186/1757-1626-2-69
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author Tamhankar, Parag M
Suvarna, Jyoti
Deshmukh, Chandrahas T
author_facet Tamhankar, Parag M
Suvarna, Jyoti
Deshmukh, Chandrahas T
author_sort Tamhankar, Parag M
collection PubMed
description An eleven month old girl presented with chronic urticaria since three months of age. There was a generalised hyperpigmented maculo-papular rash. Darier sign was positive. The skin biopsy showed plenty of spindle shaped mast cells with eosinophilic cytoplasm infiltrating the dermis and the appendiceal structures. The diagnosis of cutaneous mastocytosis (urticaria pigmentosa) was made. The child received symptomatic relief with chronic oral hydroxyzine and ranitidine therapy. Automated epinephrine self-injectors usually prescribed in this condition for self-management of anaphylactic episodes were not available. Intramuscular administration of (1:1000) diluted adrenaline via a disposable tuberculin syringe was taught to the mother. A medical bracelet containing her diagnosis and instructions in emergency was custom-made for her.
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spelling pubmed-26511152009-03-05 Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report Tamhankar, Parag M Suvarna, Jyoti Deshmukh, Chandrahas T Cases J Case Report An eleven month old girl presented with chronic urticaria since three months of age. There was a generalised hyperpigmented maculo-papular rash. Darier sign was positive. The skin biopsy showed plenty of spindle shaped mast cells with eosinophilic cytoplasm infiltrating the dermis and the appendiceal structures. The diagnosis of cutaneous mastocytosis (urticaria pigmentosa) was made. The child received symptomatic relief with chronic oral hydroxyzine and ranitidine therapy. Automated epinephrine self-injectors usually prescribed in this condition for self-management of anaphylactic episodes were not available. Intramuscular administration of (1:1000) diluted adrenaline via a disposable tuberculin syringe was taught to the mother. A medical bracelet containing her diagnosis and instructions in emergency was custom-made for her. BioMed Central 2009-01-20 /pmc/articles/PMC2651115/ /pubmed/19154597 http://dx.doi.org/10.1186/1757-1626-2-69 Text en Copyright ©2009 Tamhankar et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tamhankar, Parag M
Suvarna, Jyoti
Deshmukh, Chandrahas T
Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report
title Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report
title_full Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report
title_fullStr Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report
title_full_unstemmed Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report
title_short Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report
title_sort cutaneous mastocytosis. getting beneath the skin of the issue: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651115/
https://www.ncbi.nlm.nih.gov/pubmed/19154597
http://dx.doi.org/10.1186/1757-1626-2-69
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