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Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report
An eleven month old girl presented with chronic urticaria since three months of age. There was a generalised hyperpigmented maculo-papular rash. Darier sign was positive. The skin biopsy showed plenty of spindle shaped mast cells with eosinophilic cytoplasm infiltrating the dermis and the appendicea...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651115/ https://www.ncbi.nlm.nih.gov/pubmed/19154597 http://dx.doi.org/10.1186/1757-1626-2-69 |
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author | Tamhankar, Parag M Suvarna, Jyoti Deshmukh, Chandrahas T |
author_facet | Tamhankar, Parag M Suvarna, Jyoti Deshmukh, Chandrahas T |
author_sort | Tamhankar, Parag M |
collection | PubMed |
description | An eleven month old girl presented with chronic urticaria since three months of age. There was a generalised hyperpigmented maculo-papular rash. Darier sign was positive. The skin biopsy showed plenty of spindle shaped mast cells with eosinophilic cytoplasm infiltrating the dermis and the appendiceal structures. The diagnosis of cutaneous mastocytosis (urticaria pigmentosa) was made. The child received symptomatic relief with chronic oral hydroxyzine and ranitidine therapy. Automated epinephrine self-injectors usually prescribed in this condition for self-management of anaphylactic episodes were not available. Intramuscular administration of (1:1000) diluted adrenaline via a disposable tuberculin syringe was taught to the mother. A medical bracelet containing her diagnosis and instructions in emergency was custom-made for her. |
format | Text |
id | pubmed-2651115 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26511152009-03-05 Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report Tamhankar, Parag M Suvarna, Jyoti Deshmukh, Chandrahas T Cases J Case Report An eleven month old girl presented with chronic urticaria since three months of age. There was a generalised hyperpigmented maculo-papular rash. Darier sign was positive. The skin biopsy showed plenty of spindle shaped mast cells with eosinophilic cytoplasm infiltrating the dermis and the appendiceal structures. The diagnosis of cutaneous mastocytosis (urticaria pigmentosa) was made. The child received symptomatic relief with chronic oral hydroxyzine and ranitidine therapy. Automated epinephrine self-injectors usually prescribed in this condition for self-management of anaphylactic episodes were not available. Intramuscular administration of (1:1000) diluted adrenaline via a disposable tuberculin syringe was taught to the mother. A medical bracelet containing her diagnosis and instructions in emergency was custom-made for her. BioMed Central 2009-01-20 /pmc/articles/PMC2651115/ /pubmed/19154597 http://dx.doi.org/10.1186/1757-1626-2-69 Text en Copyright ©2009 Tamhankar et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Tamhankar, Parag M Suvarna, Jyoti Deshmukh, Chandrahas T Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report |
title | Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report |
title_full | Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report |
title_fullStr | Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report |
title_full_unstemmed | Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report |
title_short | Cutaneous mastocytosis. Getting beneath the skin of the issue: a case report |
title_sort | cutaneous mastocytosis. getting beneath the skin of the issue: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651115/ https://www.ncbi.nlm.nih.gov/pubmed/19154597 http://dx.doi.org/10.1186/1757-1626-2-69 |
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