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Genetic Variation in ATP5O Is Associated with Skeletal Muscle ATP50 mRNA Expression and Glucose Uptake in Young Twins

BACKGROUND: Impaired oxidative capacity of skeletal muscle mitochondria contribute to insulin resistance and type 2 diabetes (T2D). Furthermore, mRNA expression of genes involved in oxidative phosphorylation, including ATP5O, is reduced in skeletal muscle from T2D patients. Our aims were to investig...

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Detalles Bibliográficos
Autores principales:	Rönn, Tina, Poulsen, Pernille, Tuomi, Tiinamaija, Isomaa, Bo, Groop, Leif, Vaag, Allan, Ling, Charlotte
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651471/ https://www.ncbi.nlm.nih.gov/pubmed/19274082 http://dx.doi.org/10.1371/journal.pone.0004793

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