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The stimulation of mitogenic signaling pathways by N-POMC peptides

The N-terminal fragment of pro-opiomelancortin (POMC) has been shown previously to act as an adrenal mitogen. However, little is known about the molecular mechanisms by which mitogenesis is stimulated, although it has been shown that N-POMC(1–28) stimulates the ERK pathway in human H295R cells. We h...

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Detalles Bibliográficos
Autores principales: Pepper, David J., Bicknell, Andrew B.
Formato: Texto
Lenguaje:English
Publicado: North Holland Publishing 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651482/
https://www.ncbi.nlm.nih.gov/pubmed/18950678
http://dx.doi.org/10.1016/j.mce.2008.09.021